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Activating cgas-sting axis contributes to neuroinflammation in cvst mouse model and induces inflammasome activation and microglia pyroptosis

Longitudinal data from the Parkinsons Progression Markers Initiative (PPMI) cohort further demonstrate that AQP4 genetic variation influences glymphatic efficiency, with the rs162009 variant emerging as a prognostic marker for cognitive decline in PD ( Further genetic evidence also underscores astrocytic vulnerability in PD