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Description

In the OPC-like compartment, NTRK2 expression correlated with postsynaptic organization, axon guidance, neuronal projection guidance, neuronal migration, ERK signalling cascades and the AKT signalling cascade, consistent with the hypothesized role of TrkB in neuron-to-glioma synapses, consequent effects of AMPAR-mediated synaptic signalling on tumour migration 29 and expected signalling consequences of TrkB activation

Considering the importance of peroxisomes in ether phospholipid synthesis, lipidomic analysis was performed with two cancer cell lines, the OVCAR-8 and 786-O cell lines, in which the expression of PEX10 or FAR1 had been abrogated