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[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Kumar MA, Baba SK, Sadida HQ, Marzooqi SA, Jerobin J, Altemani FH, et al

In addition, the enhanced expression and activity of HO-1 by glutathione was associated with an increase in the total protein expression of Nrf2 and its phosphorylation at serine 40 (p-Nrf2), whereas the expression of Keap1, a negative regulator of Nrf2, was reduced in a glutathione treatment concentration-dependent manner (Figure 3A)

Nevertheless, due to continuous emission and accumulation, both organic and inorganic As have been reported in higher concentration from aquatic environments compared to terrestrial environments (IPCS 2001)