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Located in Halifax, Nova Scotia, Appili is developing novel approaches to treat infectious diseases

As TPE-DCV shifts its emission wavelength upon reacting with thiols, we collect the fluorescence signals of the cell images from both green (438521 nm) and yellow channels (522581 nm)

Together with the pharmacodynamic data, this PK knowledge may help in selecting dosing regimens needed to achieve target exposures that maximize efficacy and minimize toxicity, advancing the translation of 7,8-DHF therapy from preclinical to clinical studies

While promoting angiogenesis, collagen organization, and the balance of anti-inflammatory cytokines, it keeps endothelial integrity