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doi: 10.3892/ol.2018.9340 88

Es wird empfohlen, whrend der Infusionsbehandlung auf eine ausgewogene Ernhrung und ausreichend Flssigkeitszufuhr zu achten

High-dose methotrexate has been shown to cause kidney impairment in 210% of patients (Widemann 2014)

Second, the increase in HPA-axis sensitivity and reactivity occurring during adolescence may promote an increase in metabolic demand and the generation of ROS, leading to a compensatory increase in the activity of detoxifying enzymes in females [25]