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References Xiaoyu W, Yuxin X, Li L (2024) The effects of different intermittent fasting regimens in people with type 2 diabetes: a network meta-analysis

7.2.2 Fuel selection and combustion efficiency The fuel source exerts profound influence on PAH formation: Clean fuel hierarchy: Electric and gas grills (best): Cleanest combustion, minimal smoke generation, easy temperature control White charcoal (binchotan-style): High-carbon content, produces minimal smoke once ignited, maintains steady heat Quality hardwood charcoal: Moderate smoke production, acceptable if fully ignited before cooking begins Raw hardwood: High smoke generation but potentially acceptable for brief smoking if proper species selected Low-quality charcoal, softwoods, treated wood (poor): High smoke, variable combustion, potential chemical contaminants Plastics, tires, petroleum products (unacceptable): Extremely high PAH levels, heavy metals, dioxins Practical transitions: In African contexts, electric grills face barriers of electricity access and high capital costs

Similarly, in a screen of mutant KRAS lung adenocarcinoma cells, HG106 was found to specifically inhibit SLC7A11 function and decrease tumor burden in vivo via ROS induction and mitochondrial and endoplasmic reticulum dysfunction (78)

Hydration and elimination: Adequate fluids and fiber help excrete detoxified compounds through bile and urine