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In contrast, a high intake of zinc could reduce mucosal ROS production and improve colonic symptoms in IBD (139)

Niki E, Yoshida Y, Saito Y, Noguchi N

Another cross-sectional study using an electronic medical record database found that lower serum UA levels increased the incidence of PD, sped up the disease course, and aggravated motor problems and cognitive impairment with long-term dopaminergic medication (Dnu et al., 2022)

Experimental verification showed that the inhibition of the mitochondrial ROS-mediated pathway enhances insulin production from pancreatic cells [88], subsequently causing ferroptosis due to the accumulation of lipid peroxides [89]