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In human hippocampal progenitor cells, the IL-1-induced increases in KP enzymatic activity and the subsequent dampening of neurogenesis was reversed with co-treatment with a KMO inhibitor, which would reduce the levels of 3-HK and QA [116]

Functionally, H 2 O 2 serves as a signaling molecule in cellular transduction, regulating processes such as cell proliferation and apoptosis, while participating in immune defense by aiding pathogen elimination [76]