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10.1016/j.jid.2022.01.005 47 DavidE.UngarB.Renert-YuvalY.FacherisP.Del DucaE.Guttman-YasskyE

1 Contrary to normal cells, cancer cells are characterized by significantly increased levels of ROS owing to their unrestrained growth and increased metabolism

Similarly, oral acute toxicity tests at 3,000 mg/kg and 5,000 mg/kg resulted in no deaths, suggesting an LD 50 greater than 5,000 mg/kg, classifying it as practically non-toxic and safe (709)