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And, by the time the patient awakes in the morning, the blood levels could be expected to have fallen more than they would have had the patient taken the drug at bedtime

It was originally developed by Metabolic Pharmaceuticals in Australia during the late 1990s as a potential **anti-obesity peptide** that could stimulate fat loss without the growth-promoting or diabetogenic effects of full-length growth hormone

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Bifunctional PEGylated exenatide-amylinomimetic hybrids to treat metabolic disorders: an example of long-acting dual hormonal therapeutics