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Centrally, PNIs lead to retraction of synaptic inputs from motoneuron somata and dendrites (Alvarez et al., 2011

Unlike traditional opiates, DSIP does not induce dependency, making it a safer alternative for managing chronic pain ( 7 )

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It's important to note that while NR is generally recognized as a dietary supplement in the US, the FDA has indicated that NMN is excluded from the dietary supplement definition