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Although the exact mouth ulcers cause is still to be found and can vary from person to person, here are some common causes: Bacteria, viral, or fungal infection Irritation Allergic reaction Smoking or eating tobacco Systemic diseases like autoimmune conditions, hormonal changes, gastric or renal issues Stress Citrus fruits or acid and spicy foods Cheek and tongue-biting Braces or poor-fitting dentures and other apparatus Medications including painkillers and beta-blockers A deficient filling Genetic factors Nutritional deficiency Bottom Line Aside from causing pain or discomfort, mouth ulcers are usually harmless and can go away on their own in a week or so

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