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The core domain, UBA domains and their linkers form a loop structure that is anchored by interactions between the C-terminal helices and the core

Dadhania VP, Trivedi PP, Vikram A, Tripathi DN (2016) Nutraceuticals against neurodegeneration: a mechanistic insight

Hepatology 37 , 824832 (2003)

Nicotinamide Adenine Dinucleotide, or NAD+, is the second most abundant molecule in the body after water and plays a critical role in supporting many biological processes within your body