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Results indicate that KDC decreases the relative abundance of the Danitaceae family, while FBT reduces the Firmicutes to Bacteroidetes ratio and enhances the relative abundance of Bifidobacterium, suggesting their role in mitigating metabolic syndrome features in mice on a HFD-fat diet by modulating the gut microbiota

The gene has been identified in 1999 and annotated on chromosome 10 (Halestrap and Price, 1999)

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

Compounds such as grape seed proanthocyanidins (GSPs) have demonstrated protective effects against DPN by alleviating endoplasmic reticulum stress and enhancing antioxidant defenses