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The levels of IgE significantly declined by FAHF-2 treatment and persisted at 5 weeks post-therapy [33]

However, clear clinical evidence demonstrating that cell therapy products can modify synovial macrophage polarization, reduction of pro-inflammatory cytokines, or secretome-mediated effects relies on the extensive in vitro and in vivo translational work performed with animal models and in laboratories

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Fibroblasts migrate to the tear to initiate collagen deposition and structural reinforcement