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Despite their widespread use, chemical controls pose risks such as pesticide resistance, environmental contamination, and potential harm to human health (FAO 2019)

While some participants reported temporary skin lightening after IV infusions, the study found that 32 per cent experienced adverse reactions, including liver dysfunction and even a case of anaphylaxis

Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

Human trials show modest, inconsistent, and non-durable lightening, with effects fading after treatment stops and much of the research being small or industry-linked