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The through-line in all of these is a familiar mechanism of hype: a real but limited laboratory observation is amplified, stripped of its qualifiers, sometimes attributed to the wrong molecule (AHK-Cu results claimed for GHK-Cu), and then presented with a precise-sounding statistic that implies clinical certainty

To experimentally assess the functional consequences of our nrf2a5 mutated allele, we tested its ability to activate the transcription of an ARE-driven firefly luciferase reporter gene following a previously published protocol (Mukaigasa et al, 2012)