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Morgan ET, Koop DR, Coon MJ: Comparison of six rabbit liver cytochrome P450 isozymes in formation of a reactive metabolite of acetaminophen

Therefore, hepatocytes in the centrilobular area produce more NAPQI and deplete GSH faster than cells in the periportal area 25,26

Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography

In the recently completed parallel-group phase 1 clinical trial, the AFF008 study series assessed the tolerability and safety of repeated subcutaneous administration of a synthetic -syn mimicking epitope called AFFITOPE PD01A in a group of 24 patients randomized to receive either AFFITOPE PD01A low dose or high dose (NCT01568099)