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Effect of NNMT inhibitor on adipocyte differentiation quantitated with oil red O staining 3T3-L1 cells were cultured in 60 mm diameter dishes (8.410 4 cells/dish) and treated with NNMT inhibitor dissolved in culture media with/without adipogenic factors (1 mM IBMX, 1 M dexamethasone, 10 g/ml of insulin) during each of the scheduled media changes during the differentiation process (described above)

(4) The researchers applied the peptide in the picomolar to nanomolar range and observed that it may upregulate the proliferation of dermal papilla cells, a specialized fibroblast population that plays a central role in hair follicular biology

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It is not an FDA approved weight loss drug, so we never position it like a replacement for FDA approved obesity medications