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According to the applicant, VANFLYTA also does not target other kinases

This suggests that AD may play an anti-inflammatory role in RA by inhibiting the activation of MAPK pathway

Indeed, the state of the mucosa is influenced not only by aggressive factors but also by protective factors (mucus, mucins, epithelial cell regeneration, blood circulation, etc.), the influence of which plays a significant role in both preventing and treating inflammatory and erosive lesions of the gastrointestinal mucosa (Pennelli et al., 2020