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Description

However, in our cryo-EM structure of MARV LVP35 complex determined here, four mVP35 molecules with different lengths have been observed and each assumes as a distinct conformation, similar to the tetrameric assembly of eVP35 in the EBOV LVP35 complex structures 8,9 , which suggests that the assembly of the polymerase complex is highly conserved among the filoviruses

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This is supported in a study by Brignardello et al [214] that looked at gut permeability in asymptomatic, non-smoking obese volunteers and observed no differences compared to healthy controls

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