dihexa analog of angiotensin iv AngIV-Analog Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway Dihexa (also known as PNB-0408)
Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive Antidementia Agents The Journal of Pharmacology and Experimental Therapeutics dihexa human trial Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects Angiotensin IV does not exert prothrombotic effects in vivo ScienceDirect
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