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Lextrait de chardon-marie (Silybum marianum) contient un mlange de substances actives antioxydantes et hpatoprotectrices, appel sylimarine (dont la plus active et la plus prsente est la sylibine), ayant la proprit dactiver la GPX, une enzyme faisant partie de la premire ligne de dfense antioxydante de lorganisme (cf ci-dessus)

Similarly, A1 astrocyte activation, along with lactate-mediated lactylation, has been noted to occur in the early stages of IS

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10.1038/s41467-023-40036-z 230 YangC.XuY.ZhangW.MaM.WangS.ChaiL.et al (2021)