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utilized HCT 15, HCT 116 (human colon adenocarcinoma cells), and Hep G-2 (human laryngeal carcinoma cells) as experimental models to investigate the synergistic anticancer activity of curcumin and catechin (Manikandan et al., 2012)

Their substrate specificity is influenced by expression patterns, spatial localization and interactions with specific factors in different cellular microenvironments

Yet its close relationship with weedy relatives means that any genetic intervention must be handled carefully to avoid unintended consequences (Priyadarsini et al., 2025)