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Beth tells you that she gets irritable easily, can be aggressive at times, is highly sensitive to loud noises, and has trouble distinguishing social cues

Succinate The normally functioning SDH enzyme is localized in the inner mitochondrial membrane and plays a role in the electron transport chain as well as the conversion of succinate into fumarate

The DHFR gene is located at 5q14.1 and encodes dihydrofolate reductase

doi: 10.3389/fcell.2022.806081 Received 31 October 2021 Accepted 03 February 2022 Published 03 March 2022 Volume 10 - 2022 Edited by Xiongwen Chen, Temple University, United States Reviewed by Qian Xiang, Peking University First Hospital, China Jamal Bouitbir, University of Basel, Switzerland Updates Copyright 2022 Zhang, Qu, Chen, Luo, Chen, Xiao, Ding, Zhao, Lu, Chen and Yu