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9 Upon loss of membrane asymmetry, PS translocates across the bilayer and interacts with a new set of extracellular serum proteins and PS receptors that trigger an array of biochemical and immunological responses

In an embodiment, compositions as described herein may be administered orally

Shaking creates foam and the mechanical stress can shear the peptide chains, rendering them useless

Additional metabolites such as capsiate (which activates TRPV1 to upregulate Gpx4 and inhibit ferroptosis)[21], petroselinic acid (which activates the AMPK-mTOR pathway to suppress apoptosis)[173], and Indole-3-lactic acid (which enhances epithelial stem cell function through YAP and Nrf2 activation and protects the gut-vascular barrier through AhR/Nrf2/STAT3-mediated claudin-2 downregulation)[174, 175]