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Sulforaphane selectively triggers apoptosis in GBM cells through activation of the ATF4CHOP axis [129], whereas the proteasome inhibitor marizomib upregulates ERS markers such as GRP78, IRE1, and CHOP to induce caspase-3-dependent apoptosis, independent of ROS and autophagy [130]

Kotronen A, Seppala-Lindroos A, Vehkavaara S, Bergholm R, Frayn KN, Fielding BA, Yki-Jarvinen H (2009) Liver fat and lipid oxidation in humans

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Canagliflozin (Cana), an anti-diabetes drug, also promotes the system Xc-/GPX4 axis to inhibit ferroptosis, attenuating cardiovascular diseases (Du et al