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533 Topical agents such as the capsaicin 8% patch provide localized pain relief by desensitizing nociceptive fibers, while the lidocaine patch 5% is useful for focal neuropathic pain with a favorable safety profile

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Many patients find BPC-157 therapy cost-effective compared to prolonged physical therapy, multiple specialist visits, or the indirect costs of chronic pain and disability.

The angiogenesis hypothesis may provide new insights by suggesting a decline in angiogenic growth factors with age, which in turn leads to a reduction in microcirculation in the body (Ambrose 2016)