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The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

Your care team can suggest a sensible cadence based on your plan and how you respond, and will keep your expectations grounded throughout

Therapeutic potential of PKC inhibitors in painful diabetic neuropathy