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normal cells

10.2147/DDDT.S284163 79 XuC.SunL.RenF.HuangP.TianZ.CuiJ.et al (2020)

DAMPs: damage associated molecular patterns

In contrast, 12/15-LOX, found in endothelial cells, VSMCs, macrophages, and platelets, oxidizes arachidonic acid to 12-HETE and 15-HETE, leading to LDL oxidation, foam cell formation, and endothelial dysfunction