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As a Medical consultant , a leading nutrition expert notes , Vitamin B12 deficiency can have serious health consequences, especially for older adults and those following a plant-based diet. When Oral Supplements Arent Enough Oral supplements work for many, but not all

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Research suggests that adenosylcobalamin can support methylcobalamin's role in the methylation cycle better than the synthetic form of B12, cyanocobalamin, as it must be converted into adenosylcobalamin and methylcobalamin first, a process that may interfere with the cycle and make the methylation pathway less efficient for individuals with B12-related polymorphism