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Casares, F., Bender, W., Merriam, J., and Sanchez-Herrero, E., "Interactions of Drosophila Ultrabithorax Regulatory Regions with Native and Foreign Promoters", Genetics 145: 123-137 (1997)

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The net effect of giving furosemide is that the horse loses some weight, but most of that is reflected as a loss of water from the colon, secondary to movement of fluid from the colon into the circulation and cells to replace the fluid lost initially due to the diuretic action of the furosemide. While furosemide has been long used to combat the effects of EIPH, diligent management of the barn environment is critical as well