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doi: 10.1155/2020/1452696 [DOI] [PMC free article] [PubMed] [Google Scholar] 89

48 , e218 (2016)

We next wanted to understand how GlyNAC works. For this, the team conducted a second study in aged mice to investigate mitochondrial dysfunction, glutathione levels, oxidative stress and other hallmarks of aging specifically in the animals heart, liver and kidneys, and determined the effect of supplementing GlyNAC on these cellular defects

CMS121, a fisetin derivative, partially inhibits fatty acid synthase (FASN), thereby reducing peroxidation-prone polyunsaturated fatty acids and subsequent lipid peroxidation