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1 Introduction Psoriasis is a chronic inflammatory papulosquamous skin disease that affects approximately 60 million adults and children and is carries an increased risk of comorbidities, such as depression, psoriatic arthritis, cardiovascular disease, type 2 diabetes, obesity, and hypertension ( IL-23 consists of the p40 and p19 subunits linked by a disulfide bond

Mice were exposed to intravenous injection of Cy5-labeled SP and Cy5-labeled SP@M, respectively, and then subjected to in vivo imaging

Its so common that patients often dont recognize the symptoms (bloating, irregular digestion, food sensitivities, brain fog) as gut-related until after treatment