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Iron can cause cell stress and atrophy through toxic free reactive oxygen species, that in turn cause damage to DNA

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Asian journal of andrology 12 , 880889, doi:10.1038/aja.2010.9 (2010)

This pathway also exerts influence over the TRAIL pathway via its control over DR5, which induces apoptosis ( Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding authors