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With the exceptions of exotoxins secreted by enteropathogenic bacteria, such as the clostridial exotoxins or botulinum exotoxins discussed below, most endotoxins of commensal bacteria are not absorbed by the intact intestine of healthy individuals [49, 55]

Most efficacy data comes from manufacturer-sponsored studies and in silico computational modeling, with independent validation studies notably scarce in peer-reviewed literature

doi: 10.1007/s40261-020-00964-w 20 KimJCLeeES

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