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The cream format allows for sustained release of the active ingredients, making it ideal for overnight treatments or as part of your daily moisturising routine

4) Underexplored therapeutic strategies and model limitations: Preclinical studies have relied on in vitro mesangial cell models and lack validated animal models that fully recapitulate human IgA nephropathys pathological features (e.g., glomerular IgA1 deposition and mesangial proliferation)

2.11 Enzyme-linked immunosorbent assay (ELISA) for cytokine quantification The levels of pro-inflammatory cytokines TNF- and IL-1 in the culture supernatant of SH-SY5Y cells were quantified using ELISA kits (R&D Systems, Inc., Minneapolis, United States)