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Modalities such as Platelet-Rich Plasma (PRP) therapy, targeted nutritional interventions, and approved medications can provide similar benefits

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However, its still possible to be deficient, especially if you: have certain medical conditions, such as pernicious anemia and Crohns disease take certain medications, such as proton pump inhibitors follow a strict vegan or vegetarian diet The following symptoms may signal youre not getting enough B vitamins: fatigue weakness dyspnea (shortness of breath) heart palpitations loss of appetite headaches mouth ulcers swollen tongue irritability depression indigestion diarrhea cognitive changes, such as confusion and memory problems Speak with a healthcare professional if you experience any of these symptoms

Am J Respir Crit Care Med 182(11):13441351 Dorecka M, Siemianowicz K, Francuz T, Garczorz W, Chyra A, Klych A et al (2013) Exendin-4 and GLP-1 decreases induced expression of ICAM-1, VCAM-1 and RAGE in human retinal pigment epithelial cells