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Previous studies by our group and others have shown that non-degradative ubiquitination modifications may alter protein activity, subcellular localization, and protein-protein interactions, etc, playing a key role in a variety of cellular processes, including cell signaling, DNA damage repair, cell cycle regulation, and immune responses [46, 47]

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These changes hinder nutrient and water uptake, further intensifying stress, as observed in various plants under stress conditions [10, 40, 41]

This timing takes advantage of the bodys natural post-overnight fast state when insulin levels are low and fatty acid mobilization is already elevated