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According to the authors: These results suggest that hot flashes are linked to low-grade systemic inflammation in postmenopausal women.[ref] Leaky gut and hot flashes: Another study found that hot flush intensity may be related to increased intestinal barrier permeability (also known as leaky gut)

Especially RBD is associated with a more severe PD course of the disease, earlier motor complications and cognitive decline, indicating that RBD represents a progression marker in PD [157, 176]

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Another important consideration is the quantitative interpretation of nanoparticle performance