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A critical mechanism by which tumors achieve immune evasion involves the suboptimal expression of major histocompatibility complex (MHC) molecules and components of the antigen processing machinery (APM), such as LMP2 (large multifunctional peptidase 2), LMP7 (large multifunctional peptidase 7), TAP (transporter associated with antigen processing), and tapasin [121,122,123]

Although the list of HDlike genetic etiologies has grown considerably during the past few years, NPC is neither routinely considered in the differential diagnosis of chorea nor among the HDlike disorders

The most commonly seen HHVs in clinical practice are human herpes viruses types 1 and 2 (HHV-1 and HHV-2), more commonly known as herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2), and varicella-zoster virus (VZV)

The mucus becomes less viscous and easier to expectorate