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Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk

Researchers should review all other medications being used and seek medical guidance if needed

Otherwise, healthy ruminantseven those who are raised on factory farms (or rather, CAFOs)only require cobalt mineral in order to get their vitamin B12, and in order to thrive

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