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GSH and thioredoxin also inhibit ferroptosis (Yang et al, 2014

This leads to a state known in functional medicine as "overmethylation," characterized by severe anxiety, panic attacks, insomnia, heart palpitations, and a "wired but tired" feeling

doi: 10.1016/j.jtemb.2005.07.007 82 GarnierC.DevredF.ByrneD.PuppoR.RomanA

Drugs.com advises that people who take deferiprone or simeprevir should avoid milk thistle supplements, given the risk of abnormal liver function tests and acute liver injury