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Contribution of RhopH2 and RhopH3 to NPP The CLAG3 proteins are synthesized toward the end of the parasite asexual cell cycle, where they are stored in the rhoptry organelle in a complex, termed the RhopH complex, with two unrelated proteins named RhopH2 and RhopH3, which are encoded by single copy genes [( Plasmodium species, although the number of Clag genes varies among Plasmodium species

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Gene-environment interactions within a precision environmental health framework

High levels of intracellular amino acids activate mTORC1, and, in turn, mTORC1 activation regulates amino acid availability through downstream signaling effectors (Figure 2)