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Dysregulation or inappropriate activation of these signaling pathways can occur due to genetic mutations, infections, or other triggers, leading to an uncontrolled and amplified cytokine response

Although the degree of inflammation in OA is generally lower than in rheumatoid arthritis, synovial tissue can still exhibit marked hyperplasia and inflammatory cell infiltration (1)

In conclusion, EMS primarily reduces oocyte quality by causing GCs apoptosis, inflammation, oxidative stress, steroidogenesis disorders, and abnormal mitochondrial energy metabolism, which also provides a therapeutic direction for improving assisted reproductive technology success rates in EMS patients

Additionally, patients with liver failure caused by adjuvant therapy during the perioperative period of HCC may be considered for a liver transplant