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Litifilimab (BIIB059), a promising investigational drug for cutaneous lupus erythematosus

Factors such as dietary B12 intake, baseline B12 stores, concurrent medications, and individual absorption capacity all influence whether deficiency develops

The half-life can usually be approximated at 80 hours, unless it is known (from pharmacokinetic calculation)

In the osteoporosis trials, 1 (less than 0.1%) to 9 (0.2%) patients treated with Reclast and 0 (0%) to 1 (less than 0.1%) patient treated with placebo developed iritis/uveitis/episcleritis