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Figure A shows the positive trend in reduced re-conviction rates between 2014 and 2021 for the individuals who completed the program

Extracellular ATP, often released from damaged cells, binds to the P2X7 receptor, inducing potassium efflux and leading to NLRP3 activation [35]

2 Materials and methods 2.1 Experimental mouse models In the acute SCI model, adult male C57BL/6N mice (1012 weeks, male, Nihon SLC, Shizuoka, Japan) were subjected to contusion injury at T9T10 using an Infinite Horizon Impactor (60 kdyn) or sham-operated by laminectomy only, as described previously (Figure 1A) (Scheff et al., 2003)

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