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The changing faces of glutathione, a cellular protagonist

Bibcode:2011JAChS.13311557M

38 In the absence of PTP1B, the decrease in ROS-mediated activation of JNK and p38 MAPK and the increase in IGFIR tyrosine phosphorylation might act in conjunction with the effects on the GSK3 /Src-Fyn axis, resulting in attenuated oxidative stress and increased cell survival in response to APAP