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Some of the signs, symptoms and complications of Anti-MDA5 DM include: Higher risk for interstitial lung disease (ILD) including rapidly progressive interstitial lung disease (RP-ILD) Increased risk of pneumomediastinum air in the space between the lungs and around the heart Lower incidence of myositis Skin ulceration overlying Gottrons papules , Gottrons sign , the side of the fingernails and fingertips Painful reddish or violet coloured skin patches and firm raised spots, predominantly over the finger creases and palms Lower incidence of muscle inflammation Prominent nonscarring hair loss Mechanics hands a roughening and cracking of the skin of the tips and sides of the fingers Eyelid swelling Oral ulcers Arthritis Psoriasis-like rashes (scaly, itchy, dry skin patches) Inflammation of the fat lying just under the skin (panniculitis) Fever Fatigue Antisynthetase Syndrome Some people with Dermatomyositis or Polymyositis may also have a further complication, Antisynthetase Syndrome

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For adults, the sleep recommendations are between seven to nine hours per night