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58 Interestingly, the expression of this enzyme does not fulfill an instantaneous snapshot of the blood toxicity, but an average value over a time span of about 2/3 months (corresponding to the mean life of the erythrocyte) as it is exclusively expressed during erythropoiesis

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Actas Dermosifiliograficas in February 2023, notes that more research is needed on oral collagen supplementations benefits to the skin, since generally small studies have been done mostly on female participants